Patrick Irving

Staff

I partner with experimentalists to develop chemical probing and software tools that enable new ways of thinking about and gaining insight into RNA structure and biology. I strive to make these tools rigorous, simple to use, and well documented. As lab manager and IT guy, I help the lab to function productively and safely.

Publications

160. Y. Xiang, W. Huang, L. Tan, T. Chen, Y. He, P.S. Irving, K.M. Weeks, Q.C. Zhang and X. Dong, Pervasive downstream RNA hairpins dynamically dictate start-codon selection. Nature. 621, 423–430 (2023)

159. P.S. Irving and K.M. Weeks, RNAvigate: Efficient exploration of RNA chemical probing datasets. bioRxiv 2023.04.25.538311 (2023).

147. R.K. Przanowska, C.A. Weidmann, S. Saha, M.A. Cichewicz, K.N. Jensen, P. Przanowski, P.S. Irving, K.A. Janes, M.J. Guertin, K.M. Weeks and A. Dutta, Distinct MUNC lncRNA structural domains regulate transcription of different promyogenic factors. Cell Rep. 38, 110361 (2022).

137. A.M. Mustoe, N.N. Lama, P.S. Irving, S.W. Olson and K.M. Weeks, RNA base-pairing complexity in living cells visualized by correlated chemical probing. Proc. Natl. Acad. Sci. USA 116, 24574-24582 (2019).